Advanced Methylation Support* n Methyl Folate ™ Optimizer is a comprehensive formula designed to support optimal methylation and homocysteine levels.* The 5-MTHF in this formula – Quatrefolic ® – is the most biologically active form of folate, allowing rapid uptake into the bloodstream.* Vitamin B12 is also provided in its active form, methylcobalamin, to further support methylation and healthy homocysteine levels.* NuMedica ® has included its Enhanced Absorption Technology ™ – a proprietary blend of AstraGin ® and BioPerine ® .* Clinical studies have shown the components of this proprietary blend to increase folate absorption by up to 50.4%.*